Ok I really wanted to figure this out so I posted on a forum that has most of RO's past rabbit breeders and got two replies. Also I was wondering if there was an update on the doe. Here is the actual forum. Im not sure if you can see it unless you join but it is
http://s4.zetaboards.com/Rabbit_Addict/topic/9694337/1/#new
And here are the replies
"yes, it can cause problems. In the dwarf breeds a small true dwarf doe can have trouble delivering larger false dwarf kits -- we had one JW doe who's largest kit was always stillborn (3 litters - each litter with one stretched, one peanut and 2 normal kits) and looked stretched. In one case the entire litter was lost, probably because the other kits died while she struggled to deliver the largest first (course she also had that litter on the wire and we didn't find them until morning).
That said, scaring people who made an honest error with horror stories isn't helpful. While I've lost kits and in the one case the whole litter, I haven't lost a doe to this. And I know plenty of alternative cases where everything worked out just fine. "
"With my Holland Lops, I have used a larger false dwarf buck with smaller true dwarf does with no ill effects. Dwarf does can have larger 'normal' kits even breeding dwarf x dwarf, so a swarf birthing a 'normal' happens pretty regularly around here without any problems.
I have also had very large false dwarf does bred to small dwarf bucks have issues with large stuck kits-- so in my experience its not really the buck/doe/dwarf/nondwarf relation between parents that has been the source of any issues, its something with each individual pregnancy. It seems that most often, the doe's body regulated growth of the fetuses inside the doe so she can give birth safely, and those that will be much bigger grow much bigger once born. When something goes wrong with that regulation, it doesn't seem to matter if the doe is bigger or smaller or the same size as the buck she was bred to.
However when breeding dwarf x non-dwarf Hollands, the largest size difference between parents has been 1 to 2 pounds. If your friend's dwarf doe is a small true dwarf or 2-3 pounds, perhaps the 8-9 pound size of an adult Rex could cause more issues.
Even so, I would be more concerned about the younger age of the doe meaning her reproductive tract was not yet as mature, than I would about the size of the buck. "