Actually metabolic issues are very common but misdiagnosed. If you check many of my previous posts, Metabolic Bone Disease (MBD) is something I have mentioned often. The name is very misleading since this condition can affect any body system. One particular organ or system can suffer metabolism issues....bones are primary. In rabbits, the kidney and liver are also very suspect to metabolic issues. We have seen brittle bones, violent seizures, organ failure and even death, In people, most metabolic issues are inherited. In animals, MBD is usually diet related. Testing for the particular metabolic issue can be challenging and sometimes, especially in animals, almost impossible.Rabbits are prone to Vitamin D and calcium deficiencies. This is due to the incorrect idea that calcium should be eliminated from a rabbit's diet. Since many of our rabbits are indoor rabbits and eat an artificial diet, there is also a Vitamin D issue. Vitamin D is acquired by either exposure to unfiltered sunlight or dietary supplements. A proper diet is essential. While it is possible to overcome some metabolic issues, in severe cases it may not be possible for a full resolution.
If you suspect metabolic issues, a full CBC and urinalysismay be of help but should be interpreted by a very experienced vet. Most small animal vets do not consider MBD since it is rarely seen in cats and dogs due to fortified food but it is something we see often in wildlife and exotics.
Randy