Here are the major ones most american school children learn about:
Pocahontas- notable for her association with the colonial settlement at Jamestown, Virginia. She was the daughter of Chief Powhatan, the head of a network of tributary tribal nations in the Tidewater region of Virginia. In a well-known historical anecdote, she is said to have saved the life of an Indian captive, Englishman John Smith, in 1607 by placing her head upon his own when her father raised his war club to execute him.
Geronimo - was a prominent Native American leader of the Chiricahua Apache who defended his people against the encroachment of the US on their tribal lands for over 25 years.
Sacajawea - Sacajawea is most well know for accompanying Meriwether Lewis and William Clark during their Corps of Discovery of the Western United States in 1806.
Squanto - Assisting the Pilgrims during their first, harsh winter, the Patuxet, Tasquantum (Squanto) befriended the group in order to see them safely through to spring.